Objective: To analyze the situation and reasons of irrational medication orders in pediatric outpatient department

so as to provide reference for promoting clinical rational drug use. Methods: A total of 847 cases of irrational medical orders in pediatric outpatient department of our hospital in 2018 were analyzed. Pareto chart was used to analyze the primary

secondary and general causes of irrational drug use. Results: The primary factors of irrational drug use were inappropriate dosage (40.61%)

inappropriate route of administration (26.92%)

improper frequency of administration (12.51%). The secondary factors were inconsistency between medication and diagnosis (7.56%). The general factors were computer input error (3.78%)

medication contraindication (3.78%)

repeated medication (1.77%)

inappropriate solvent (1.77%) and others (1.30%). Conclusion: Pharmacists should perform targeted interventions and pharmaceutical services according to the types of irrational drug use

formulate corresponding intervention measures

and control the main factors

which will help to improve the level of rational drug use. [Keywords]irrational drug use; Pareto chart; pediatrics